Journal article

Cost-effectiveness of family history-based colorectal cancer screening in Australia

DA Ouakrim, A Boussioutas, T Lockett, JL Hopper, MA Jenkins

BMC Cancer | BIOMED CENTRAL LTD | Published : 2014

Abstract

Background: With 14.234 diagnoses and over 4047 deaths reported in 2007, colorectal cancer (CRC) is the second most common cancer and second most common cause of cancer-related mortality in Australia. The direct treatment cost has recently been estimated to be around AU$1.2 billion for the year 2011, which corresponds to a four-fold increase, compared the cost reported in 2001. Excluding CRCs due to known rare genetic disorders, 20% to 25% of all CRCs occur in a familial aggregation setting due to genetic variants or shared environmental risk factors that are yet to be characterised. A targeted screening strategy addressed to this segment of the population is a potentially valuable tool ..

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